Fiji
WILLIAM ANTONIO CÁRDENAS AGUAZACO
Biomedical R&D Scientist & Quality Specialist
Bogotá,DC
Summary
With over six years of experience in Biomedical Research and Development and Quality Assurance, I am a chemist and materials scientist, holding an M.Sc. My work has focused on creating polymeric medical devices for bone and cartilage regeneration, using methods like 3D Printing, Electrospinning, and Hydrogel Synthesis. Since 2024, I have developed a strong understanding of regulatory requirements, including GMP/BPM compliance. My background also includes preclinical validation, where I have experience in writing CICUA/IACUC protocols and running in vivo and in vitro tests, such as Cytotoxicity and Immunohistochemistry. I am also certified in Clinical Trials Management, which complements my technical skills with regulatory insight.
Overview
9
9
years of professional experience
5
5
Certifications
2
2
Languages
Work History
Specialized Researcher & QA Support
IDCBIS (District Institute of Science, Biotechnology, and Innovation in Health)
12.2018 - Current
- Quality Assurance (QA) Implementation: Since mid-2024, actively managed Quality Assurance tools including Corrective and Preventive Actions (CAPAs), handling of audit findings, and Risk Analysis (ARs) to ensure strict adherence to GMP (BPM) standards for medical devices.
- Medical Device R&D: Co-developed a biocompatible construct for critical bone defects using 3D printing and electrospinning. Validated biocompatibility through cytotoxicity assays (ISO 10993) and Live/Dead staining.
- Hydrogel Development: Designed and fabricated hydrogels utilizing ionic crosslinking and freeze-thaw techniques for tissue engineering applications.
- Preclinical & Regulatory Management: Led the drafting and submission of CICUA protocols (Institutional Committee for the Care and Use of Animals), ensuring ethical compliance and approval for in vivo rabbit model trials.
- Scientific Validation: Successfully executed in vivo evaluations demonstrating device efficacy in bone lesion repair, analyzing data for high-impact scientific publication.
Junior Researcher (DANUM Research Group)
UPTC (Pedagogical and Technological University of Colombia)
01.2017 - 01.2018
- Executed research projects under the "Young Researcher" grant (Agreement 060), developing new polymeric materials.
- Conducted physicochemical and mechanical characterization of synthesized materials to assess their viability for tissue engineering.
- Mentored undergraduate students in laboratory techniques and research methodologies.
Education
Master of Science - Metallurgy and Materials Science
UPTC
Colombia07-2019
Bachelor of Science - Chemistry
UPTC
Colombia08-2016
Skills
Biological & In Vitro Assays: Cell Culture & Management, Cytotoxicity Assays (ISO 10993), Live/Dead Assays, Immunohistochemistry (IHC)
Software
R Studio
OriginPro
SPSS
Certification
DIPLOMADO EN GESTION DE ENSAYOS CLINICOS
Timeline
DIPLOMADO EN GESTION DE ENSAYOS CLINICOS
12-2025
Curso de Buenas Prácticas Clínicas – E6 (Revisión 3) y Regulación Local (Colombia)
11-2025
Specialized Researcher & QA Support
IDCBIS (District Institute of Science, Biotechnology, and Innovation in Health)
12.2018 - Current
Junior Researcher (DANUM Research Group)
UPTC (Pedagogical and Technological University of Colombia)
01.2017 - 01.2018
Master of Science - Metallurgy and Materials Science
UPTC
Bachelor of Science - Chemistry
UPTC
SELECTED PUBLICATIONS
- Exploring calcium-free alternatives in endochondral bone repair tested on in vivo trials - A review.
- Electrospun Scaffolds of Polylactic Acid, Collagen, and Amorphous Calcium Phosphate for Bone Repair.
- Preparation of potato starch microfibers obtained by electro wet spinning.
- Effects of heat treatment and collection method on the crystal structure of electrospun poly(lactic acid) nanofibers.
- Comparative Study of Starch Fibers Obtained by Electro-spinning of Indigenous, Commercial and Cationic Potato Starch
INTELLECTUAL PROPERTY
- Patent Application: Method for Manufacturing a Medical Device via 3D Printing and Electrospinning (Ref: NC2022/0002677).
- Status: Approved.